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The Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) is an NIH Protein Structure Initiative Specialized Center focused on the accelerated development, integration, and deployment of three emerging technologies (tunable laboratory X-ray source, synthetic gene design, and nanovolume microfluidic crystallization) which have high potential to improve the economics of protein structure determination by X-ray crystallographic methods.
The ATCG3D is a specialized center of the Protein Structure Initiative Research Network (http://www.nigms.nih.gov/psi) and is funded by the NIH NIGMS and NIH NCRR. |
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| 11/16/2008 | | 11/16/2008 | | 11/16/2008 | | 2/12/2008 | | 10/26/2007 | | 8/1/2007 | | 8/1/2007 | | 8/1/2007 | | 8/1/2007 | | 6/1/2006 | | 6/24/2005 | | 3/2/2005 | | 3/1/2005 | | 12/1/2004 |
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| Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC | Science | Science Magazine | 11/21/2008 | | Gerdts CJ, Elliott M, Lovell S, Mixon MB, Napuli AJ, Staker BL, Nollert P, Stewart L | Acta Crystallographica Section D: Biological Crystallography | PubMed Central | 10/18/2008 | | Singh J, Salcius M, Liu SW, Staker BL, Mishra R, Thurmond J, Michaud G, Mattoon DR, Printen J, Christensen J, Bjornsson JM, Pollok BA, Kiledjian M, Stewart L, Jarecki J, Gurney ME | ACS Chemical Biology | American Chemical Society Publications | 10/8/2008 |
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| Peter Kuhn and Ray Stevens labs at TSRI | The Kuhn and Stevens labs focus on understanding viruses and their host interactions through protein structure determination on a proteome-wide scale using advanced high-throughput structural genomics technologies, with a view to developing novel therapeutics and diagnostics.
| | Decode Biostructures and Lance Stewart | deCODE biostructures, located in Bainbridge Island, WA, is a leading provider of contract research services with capabilities that span the entire gene-to-structure landscape including gene synthesis, gene construct engineering, large-scale protein production and purification, high-throughput crystallization screening, pre-formulation screening of small molecules, X-ray diffraction data collection, model building, and refinement. | | Lyncean Technologies, Inc. | Lyncean Technologies, Inc., located in Palo Alto, CA, has developed a new generation of compact X-ray sources - miniature synchrotron light sources. These powerful home-lab-size X-ray sources will enable scientists in academics and industry to pursue state-of-the-art synchrotron radiation applications in their own laboratories. | | Ismagilov Group at the University of Chicago | The research goal of the Ismagilov Lab is to understand chemical and biological complexity, both top down at the level of systems and bottom up at the level of molecular components. Using chemistry, biological systems respond and adapt to their environments, perform fascinating functions, and even think.
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