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Accelerated Technologies Center for Gene to 3D Structure > ATCG3D Publications  

ATCG3D Publications

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Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics Use SHIFT+ENTER to open the menu (new window).
Ng JD et al.  Methods in Molecular Biology  2/27/2007ATCG3D 
Remedial strategies in structural proteomics: Expression, purification, and crystallization of the Vav1/Rac1 complexUse SHIFT+ENTER to open the menu (new window).
Brooun A, Foster SA, Chrencik JE, Chien EYT, Kolatkar AR, Streiff M, Ramage P, Widmer H, Weckbecker G, Kuhn PProtein Expression and Purification1/5/2007ATCG3D
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteinsUse SHIFT+ENTER to open the menu (new window).
Liang Li, Debarshi Mustafi, Qiang Fu, Valentina Tereshko, Delai L. Chen, Joshua D. Tice, and Rustem F. Ismagilov PNAS12/12/2006ATCG3D
Time-Controlled Microfluidic Seeding in nL-Volume Droplets to Separate Nucleation and Growth Stages of Protein CrystallizationUse SHIFT+ENTER to open the menu (new window).
Gerdts CJ, et al    Angewandte Chemie Int. Ed Engl.  12/11/2006ATCG3D 
In situ data collection and structure refinement from microcapillary protein crystallizationUse SHIFT+ENTER to open the menu (new window).
Yadav M.K., et al.  Journal Applied Crystallography  12/14/2005ATCG3D
Reduction in diffuse-convective disturbances in nanovolume protein crystallization experimentsUse SHIFT+ENTER to open the menu (new window).
D.C. Carter, P. Rhodes, D.E. McRee, L. Tari, D.R. Dougan, G. Snell, E. Abola, R.C. StevensJ. Appl. Cryst5/1/2005
Shotgun Crystallization Strategy for Structural Genomics II: Crystals and Conditions that Produce High Resolution Structures for T. maritima ProteinsUse SHIFT+ENTER to open the menu (new window).
R. Page, S. Lesley, A. Deacon, R. C. StevensJ. Funct. Struct. Genomics4/1/2005
NMR Screening of Mouse Homolog Proteins in a Structural Proteomics PipelineUse SHIFT+ENTER to open the menu (new window).
R. Page, W. Peti, K. Moy, I. Wilson, R. Stevens, K. WuthrichProc. Natl. Acad. Sci. USA3/1/2005
Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I-DNA Covalent ComplexUse SHIFT+ENTER to open the menu (new window).
B. L. Staker, M. D. Feese, M. Cushman, Y. Pommier, D. Zembower, L. Stewart, and A. B. Burgin J. Med. Chem.2/1/2005
Whole Gene Synthesis: A Gene-O-Matic Future. Use SHIFT+ENTER to open the menu (new window).
L. Stewart and Alex B. Burgin In  Frontiers in Drug Design and Discovery. Bentham Science Publishers, Ltd,1/1/2005
Automatic classification of protein crystallization images using a curve tracking algorithmUse SHIFT+ENTER to open the menu (new window).
M. Bern, D. Goldberg, R.C. Stevens, P. KuhnJ. Appl. Cryst.8/1/2004
Protein biophysical properties that correlate with crystallization success in Thermotoga Maritima: Maximum clustering strategy for structural genomicsUse SHIFT+ENTER to open the menu (new window).
J.M. Canaves, R. Page, R.C. StevensJ. Molec. Biol8/1/2004
Mechanisms of camptothecin resistance by human topoisomerase I mutationsUse SHIFT+ENTER to open the menu (new window).
Chrencik, J. E., B. L. Staker, A. B. Burgin, P. Pourquier, Y. Pommier, L. Stewart, M. R. RedinboJ. Mol. Biol.7/1/2004
Protein structure prediction and analysis using the Robetta serverUse SHIFT+ENTER to open the menu (new window).
D.E. Kim, D. Chivian, D. BakerNucleic Acids Res.7/1/2004
Climbing Mount Everest, the GPCR wayUse SHIFT+ENTER to open the menu (new window).
Nollert, P. and L. Stewart.Drug Discovery Today6/1/2004
Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screensUse SHIFT+ENTER to open the menu (new window).
R. Page, R.C. StevensMethods5/1/2004
Improvement of Comparative Model Accuracy by Free Energy Optimization along Principal Components of Natural Structural VariationUse SHIFT+ENTER to open the menu (new window).
B. Qian, A. Ortiz, D. Baker.Proc. Natl. Acad. Sci. U.S.A.4/19/2004
Raid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MSUse SHIFT+ENTER to open the menu (new window).
D. Pantazatos, J.S. Kim, H.E. Klock, R.C. Stevens, I.A. Wilson, S.A. Lesley, V.L. Woods JrProc. Natl. Acad. Aci U.S.A.4/1/2004
Scalable high-throughput micro-expression device for recombinant proteinsUse SHIFT+ENTER to open the menu (new window).
R. Page, K. Moy, E.C. Sims, J. Velasquez, B. McManus, C. Grittini, T.L. Clayton, R.C. StevensBioTechniques4/1/2004
Automated sample mounting and alignment system for biological crystallography at a synchrotron sourceUse SHIFT+ENTER to open the menu (new window).
G. Snell, C. Cork, R. Nordmeyer, E. Cornell, G. Meigs, D. Yegian, J. Jaklevic, J. Jin, R.C. Stevens, T. Earnest Structure3/1/2004
Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specificUse SHIFT+ENTER to open the menu (new window).
B. Taneri, B. Snyder, A. Novoradovsky, T. Gaasterland.Genome Biol.2/1/2004
Long Live Structural BiologyUse SHIFT+ENTER to open the menu (new window).
R.C. StevensNature Struct. Molec. Biol.2/1/2004
A droplet-based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor-diffusion methods with on-chip x-ray diffractionUse SHIFT+ENTER to open the menu (new window).
B. Zheng, J.D. Tice, L.S. Roach, R.F. IsmagilovAngew. Chem. Int. Edit.1/1/2004
A Fully Integrated Protein Crystallization Platform for Small Molecule Drug DiscoveryUse SHIFT+ENTER to open the menu (new window).
D. Hosfield, J. Palan, M. Hilgers, D. Scheibe, D. McRee, R.C. StevensJ. Struct. Biol.5/1/2003
Shotgun crystallization strategy for structural genomics: An optimized two-tiered crystallization screen against the Thermatoga maritima proteomeUse SHIFT+ENTER to open the menu (new window).
R. Page, S.K. Grzechnik, J. Canaves, G. Spraggon, A. Kreusch, R.C. Stevens, S. Lesley.Acta Crystallogr. D4/1/2003
The cost and value of three-dimensional protein structureUse SHIFT+ENTER to open the menu (new window).
R.C. StevensDrug Discovery World3/1/2003
Robotics for Automated Crystal Formation and AnalysisUse SHIFT+ENTER to open the menu (new window).
M. Weselak, M.G. Patch, T.L. Selby, G. Knebel, R.C. StevensMethods in Enzymology. Eds. C.W. Carter & R.M. Sweet. Academic Press: San Diego CA2/1/2003
Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size dropletsUse SHIFT+ENTER to open the menu (new window).
B. Zheng, L.S. Roach, R.F. Ismagilov.J. Am. Chem. Soc.1/1/2003
The genesis of high-throughput structure-based drug discovery using protein crystallographyUse SHIFT+ENTER to open the menu (new window).
P. Kuhn, K. Wilson, M.G. Patch, R.C. Stevens Curr. Opin. Chem. Biol.5/1/2002
Blu-Ice and the distributed control system: software for data acquisition and instrument control at macromolecular crystallography beamlinesUse SHIFT+ENTER to open the menu (new window).
T.M. McPhillips, S.E. McPhillips, H.J. Chiu, A.E. Cohen, A.M. Deacon, P.J. Ellis, E. Garman, A. Gonzalez, N.K. Sauter, R.P. Phizackerley, S.M. Soltis, P. Kuhn. J. Synchrotron Radiat.4/1/2002
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipelineUse SHIFT+ENTER to open the menu (new window).
S.A. Lesley, P. Kuhn, A. Godzik, A.M. Deacon, I. Mathews, A. Kreusch, G. Spraggon, H.E. Klock, D. McMullan, T. Shin, J. Vincent, A. Robb, L.S. Brinen, M.D. Miller, T.M. McPhillips, M.A. Miller, D. Scheibe, J.M. Canaves, C. Guda, L. Jaroszewski, T.L. SelbyProc. Natl. Acad. Sci. USA4/1/2002
An approach to rapid protein crystallization using nanodropletsUse SHIFT+ENTER to open the menu (new window).
B.D. Santarsiero, D.T. Yegian, C.C. Lee, G. Spraggon, J. Gu, D. Scheibe, D.C. Uber, E.W. Cornell, R.A. Nordmeyer, W.F. Kolbe, J. Jin, A.L. Jones, J.M. Jaklevic, P. G. Schultz, R.C. StevensJ. Appl. Crystallography3/2/2002
Bioinformatics and high-throughput protein production for structural genomicsUse SHIFT+ENTER to open the menu (new window).
T.L. Selby, R.C. StevensIn: Gene Cloning and Expression Technologies, M.P. Weiner & Q. Lu (Eds)., Westborough, MA: Biotechniques Press3/1/2002
The mechanism of topoisomerase I poisoning by a camptothecin analog.Use SHIFT+ENTER to open the menu (new window).
Staker, B. L., K. Hjerrild, M. D. Feese, A. B. Burgin Jr., and L.Stewart.Proc. Natl. Acad. Sci. USA2/1/2002
High throughput crystallization and structure determination in drug discoveryUse SHIFT+ENTER to open the menu (new window).
L. Stewart, R. Clark, C. Behnke.Drug Discovery Today1/1/2002
High-throughput X-ray Crystallography for Structure-based Drug DesignUse SHIFT+ENTER to open the menu (new window).
K.E. Goodwill, M.G. Tennant, R.C. StevensDrug Discovery Today4/18/2001
Global efforts in structural genomics.Use SHIFT+ENTER to open the menu (new window).
R.C. Stevens, S. Yokoyama, I.A. WilsonScience2/1/2001
Industrializing structural biologyUse SHIFT+ENTER to open the menu (new window).
R.C. Stevens, I.A. WilsonScience1/1/2001
Automation of X-ray CrystallographyUse SHIFT+ENTER to open the menu (new window).
E. Abola, P. Kuhn, T. Earnest, R.C. StevensNature Struct. Biol.4/1/2000
Combining Structural Genomics and Enzymology: Completing the Picture in Metabolic Pathways and Enzyme Active SitesUse SHIFT+ENTER to open the menu (new window).
H. Erlandsen, E. Abola, R.C. StevensCurr. Opin. Struct. Biol.3/1/2000
High-throughput protein crystallizationUse SHIFT+ENTER to open the menu (new window).
R.C. StevensCurr. Opin. Struct. Biol.2/1/2000
Design of High-throughput Methods of Protein Production for Structural BiologyUse SHIFT+ENTER to open the menu (new window).
R.C. StevensStructure Folding and Design1/1/2000
Laser-electronic storage ring.Use SHIFT+ENTER to open the menu (new window).
Z. Huang, R.D. Ruth.Phys. Rev.1/1/1998